Pilot study of using transcranial temporal interfering theta-burst stimulation for modulating motor excitability in rat.

ABSTRACT: Transcranial temporal interference stimulation (tTIS) is a promising brain stimulation method that can target deep brain regions by delivering an interfering current from surface electrodes. Most instances of tTIS stimulate the brain with a single-frequency sinusoidal waveform generated by wave interference. Theta burst stimulation is an effective stimulation scheme that can modulate neuroplasticity by generating long-term potentiation- or depression-like effects. To broaden tTIS application, we developed a theta burst protocol using tTIS technique to modulate neuroplasticity in rats. Two cannula electrodes were unilaterally implanted into the intact skull over the primary motor cortex. Electrical field of temporal interference envelopes generated by tTIS through cannula electrodes were re

SUBMITTER: Wu CW 

PROVIDER: S-EPMC11365202 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature