Degradation of hydroxypropyl methylcellulose (HPMC) by acoustic and hydrodynamic cavitation.

ABSTRACT: The present study aims to investigate the degradation of HPMC on a laboratory scale by acoustic and hydrodynamic cavitation. The effects of temperature and the addition of an external oxidizing agent on the effectiveness of HPMC degradation were systematically investigated by SEC/MALS-RI, FTIR and ¹H NMR. The results of the experiments without cavitation show that an external oxidizing agent alone reduces the weight-average molar mass at 60 °C in 30 min for 45.1 % (from 335 to 184 kg mol^-1). However, the weight-average molar mass of HPMC decreased significantly more in the cavitation treatment, for 98.8 % (from 335 to 4 kg mol^-1) in 30 min at optimal operating conditions of hydrodynamic cavitation (i.e. addition of external oxidant and 60 °C) with a concomi

SUBMITTER: Zupanc A 

PROVIDER: S-EPMC11365383 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature