The efficiency of human fat products in wound healing: A systematic review and meta-analysis.

ABSTRACT: Wound development and healing involve intricate genetic and molecular processes, posing significant clinical management challenges. The objective of this study was to assess commonly used fat extracts' efficacy and safety (autologous fat, stromal vascular fraction and adipose-derived stem cells) in wound healing, particularly for refractory wounds, with the goal of providing evidence in clinical use. After a systematic review, 21 randomised controlled trials were included in our study. Based on the classification of human fat products, our meta-analysis revealed that the use of human fat products could speed healing rate, shorten healing time and achieve more complete healing, with statistically significant differences in outcome indicators when compared to conventional treatments. The ana

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC11365526 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature