Identification of cross-reactive IgE-binding proteins from Philippine allergenic grass pollen extracts.

ABSTRACT:

Background

Respiratory allergies are one of the most common allergic diseases that affect Filipinos. Grass pollen accounts for the majority of the outdoor allergens triggering these respiratory allergies. Cross-reactivity among the Philippine grass pollen grains has not been extensively studied.

Objective

This study aims to investigate the cross-reactivity of our local grasses and identify the cross-reactive allergens.

Methods

Grass pollen grains were collected and processed into crude allergenic extracts. The IgE-reactivity of these crude allergenic pollen extracts was studied using sera from patients who tested positive for the mentioned extracts. The proteins from the immunoblots of cross-reactive pollen allergen extracts were sequenced and identified.

Results</

SUBMITTER: Castor MAR 

PROVIDER: S-EPMC11365694 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature