Low-Dose Triple-Pill vs Standard-Care Protocols for Hypertension Treatment in Nigeria: A Randomized Clinical Trial.

ABSTRACT:

Importance

With the high burden of hypertension in sub-Saharan Africa, there is a need for effective, safe and scalable treatment strategies.

Objective

To compare, among Black African adults, the effectiveness and safety of a novel low-dose triple-pill protocol compared with a standard-care protocol for blood pressure lowering.

Design and setting

Randomized, parallel-group, open-label, multicenter trial conducted in public hospital-based family medicine clinics in Nigeria.

Participants

Black African adults with uncontrolled hypertension (≥140/90 mm Hg) who were untreated or receiving a single blood pressure-lowering drug.

Interventions

Participants were randomly allocated to low-dose triple-pill or standard-care protocols. The triple-pill protocol involv

SUBMITTER: Ojji DB 

PROVIDER: S-EPMC11366076 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature