Dataset Information

Characteristics and patient-reported outcomes of long-term cancer survivors after apatinib-based therapy: an online survey.

ABSTRACT:

Background

Data on long-term cancer survivors treated with apatinib are lacking. This study aimed to describe the characteristics of long-term cancer survivors after apatinib-based therapy, and to know about their satisfaction degree with apatinib and severity of depression and insomnia.

Methods

Patients with solid tumors who had received apatinib-based therapy for at least 5 years were invited to complete an online questionnaire. Characteristics of patients and treatment, knowledge of apatinib, satisfaction degree, and severity of depression and insomnia assessed by Patient Health Questionnaire-9 and Insomnia Severity Index were collected.

Results

Between December 8, 2023 and March 1, 2024, a total of 436 patients completed the online questionnaire. Most patients were satisfied with the efficacy (96.6%) and safety (93.1%) of apatinib, were willing to continue apatinib treatment (99.5%), and would recommend apatinib to other patients (93.3%). Continuous apatinib treatment resulted in significant negative impact on daily life, work, or study in only two (0.5%) patients. Almost all patients currently had no or mild depression (97.0%) and insomnia (97.9%) problems. The most common patient-reported adverse events were hand-foot syndrome (21.3%) and hypertension (18.3%).

Conclusions

Our survey showed a high satisfaction degree with apatinib in long-term cancer survivors. Long-term apatinib treatment resulted in almost no negative impact on patient's quality of life.

SUBMITTER: Zhang T

PROVIDER: S-EPMC11366127 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Publications

Characteristics and patient-reported outcomes of long-term cancer survivors after apatinib-based therapy: an online survey.

Zhang Tingting T Meng Chao C He Wei W Xu Tao T Yang Yi Y Tu Chongqi C Zhang Ling L Sun Xiaofeng X Zhu Chunrong C Dang Xueyi X Wang Ke K Chen Chuan C Yan Xiong X Xu Huiting H Huang Le L Jiang Enlai E Xia Feng F Zhou Xinming X Zhou Shunkai S Zang Weidong W Li Xifeng X Zhang Jin J Zheng Jiaping J Xin Jianjun J Huang Bin B Zhu Guopei G Zhu Jiexiang J Liang Jun J

BMC cancer 20240831 1

<h4>Background</h4>Data on long-term cancer survivors treated with apatinib are lacking. This study aimed to describe the characteristics of long-term cancer survivors after apatinib-based therapy, and to know about their satisfaction degree with apatinib and severity of depression and insomnia.<h4>Methods</h4>Patients with solid tumors who had received apatinib-based therapy for at least 5 years were invited to complete an online questionnaire. Characteristics of patients and treatment, knowled ...[more]

PMID: 39217302

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Dataset Information

Characteristics and patient-reported outcomes of long-term cancer survivors after apatinib-based therapy: an online survey.

Background

Methods

Results

Conclusions

Publications

Characteristics and patient-reported outcomes of long-term cancer survivors after apatinib-based therapy: an online survey.

Similar Datasets

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