Static and dynamic interactions within the triple-network model in stroke patients with multidomain cognitive impairments.

ABSTRACT:

Background

Internal capsule strokes often result in multidomain cognitive impairments across memory, attention, and executive function, typically due to disruptions in brain network connectivity. Our study examines these impairments by analyzing interactions within the triple-network model, focusing on both static and dynamic aspects.

Methods

We collected resting-state fMRI data from 62 left (CI_L) and 56 right (CI_R) internal capsule stroke patients, along with 57 healthy controls (HC). Using independent component analysis to extract the default mode (DMN), executive control (ECN), and salience networks (SAN), we conducted static and dynamic functional network connectivity analyses (DFNC) to identify differences between stroke patients and controls. For DFNC, we used k-mean

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11367478 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature