Sex specific analysis of patients with and without reported statin intolerance referred to a specialized outpatient lipid clinic.

ABSTRACT:

Background

Lowering LDL-cholesterol is a fundamental goal for both primary and secondary prevention of atherosclerotic cardiovascular diseases. Our study aims to analyse potential sex disparities regarding the tolerability and effectiveness of lipid-lowering therapy in patients with and without reported statin intolerance who are being treated at a lipid-outpatient clinic.

Methods

From 2017 to 2022, n = 1062 patients (n = 612 men, n = 450 women) at high-risk were referred to our lipid-outpatient clinic because of difficulties in lipid control by primary healthcare providers. The main therapeutic objective was to optimize lipid-lowering therapy according to current treatment guidelines.

Results

Patients presented with high LDL-C baseline levels (4.97 ± 1.81 mmol/l (192

SUBMITTER: Muck MA 

PROVIDER: S-EPMC11367976 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature