Risk factors for bloodstream infections due to carbapenem-resistant Enterobacterales: a nested case-control-control study.

ABSTRACT:

Background

Carbapenem-resistant Enterobacterales (CRE) bloodstream infections (BSIs) are a major threat to patients. To date, data on risk factors have been limited, with low internal and external validity. In this multicentre study, risk factors for CRE BSI were determined by comparison with two control groups: patients with carbapenem-susceptible Enterobacterales (CSE) BSI, and patients without Enterobacterales infection (uninfected patients).

Methods

A multicentre, case-control-control study was nested in a European prospective cohort study on CRE (EURECA). CRE BSI:CSE BSI matching was 1:1, CRE BSI:Uninfected patients matching was 1:3, based on hospital, ward and length of stay. Conditional logistic regression was applied.

Results

From March 2016 to November 2018,

SUBMITTER: Zhou H 

PROVIDER: S-EPMC11368427 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature