The first complete genome sequence and genetic evolution analysis of bovine norovirus in Xinjiang, China.

ABSTRACT:

Introduction

Viruses are among the main pathogens causing diarrhoea in calves. The current study found that bovine norovirus (BNoV) is one of the principal viruses causing diarrhoea in calves in Xinjiang, China.

Material and methods

A total of 974 calf faecal samples from six regions in Xinjiang were tested for BNoV using reverse-transcriptase PCR. The genomic characteristics of BNoV and the genetic evolution of the VP1 gene, protein three-dimensional structure characteristics and amino acid variation were analysed using bioinformatics methods.

Results

Epidemiological survey results showed that the infection rate of BNoV was 19.82%, and all samples tested positive in five regions. The results of the genetic evolution analysis showed that BNoV strains from Tacheng of n

SUBMITTER: Ma Z 

PROVIDER: S-EPMC11368483 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature