Inflammatory Burden Index as a promising new marker for predicting surgical and oncological outcomes in colorectal cancer.

ABSTRACT:

Aims

The prognosis of colorectal cancer (CRC) has been historically reliant on the Tumor Node Metastasis (TNM) staging system, but there is variability in outcomes among patients at similar stages. Therefore, there is an urgent need for more robust biomarkers. The aim of this study was to assess the clinical feasibility of the recently reported Inflammatory Burden Index (IBI) for predicting short- and long-term outcomes in patients with CRC.

Methods

This was a retrospective observational study of 555 CRC patients undergoing surgery for primary tumor resection. We determined the prognostic value of preoperative IBI for disease-free and overall survival, and its predictive value for perioperative risk of infectious complications, including surgical site infection.

Results</

SUBMITTER: Yamashita S 

PROVIDER: S-EPMC11368506 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature