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MRI assessed placental volume and adverse pregnancy outcomes: Secondary analysis of prospective cohort study.


ABSTRACT:

Introduction

Our goal was to evaluate the potential utility of magnetic resonance imaging (MRI) placental volume as an assessment of placental insufficiency.

Methods

Secondary analysis of a prospective cohort undergoing serial placental MRIs at two academic tertiary care centers. The population included 316 participants undergoing MRI up to three times throughout gestation. MRI was used to calculate placental volume in milliliters (ml). Placental-mediated adverse pregnancy outcome (cAPO) included preeclampsia with severe features, abnormal antenatal surveillance, and perinatal mortality. Serial measurements were grouped as time point 1 (TP1) <22 weeks, TP2 22 0/7-29 6/7 weeks, and TP3 ≥30 weeks. Mixed effects models compared change in placental volume across gestation betwee

SUBMITTER: Gibbins KJ 

PROVIDER: S-EPMC11368624 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature