Ambulatory Blood Pressure in Patients With Rheumatoid Arthritis: Association With Immune Activation.

ABSTRACT:

Objective

The prevalence of hypertension, a major cardiovascular risk factor, is increased in patients with rheumatoid arthritis (RA) and may be driven by immune activation. The purpose of this study was to determine if ambulatory 24-hour blood pressure (BP) is elevated in RA vs control participants and whether it is associated with immune activation.

Methods

We conducted a cross-sectional study of 46 patients with RA and 23 control participants. Participants wore an ambulatory BP monitor that obtained diurnal BP every 15-30 minutes and nocturnal BP every 30 minutes. Inflammatory mediators in plasma were measured using an inflammation proteomics panel. Differences in BP measurements were assessed by Mann-Whitney U test, and association with inflammatory mediators was

SUBMITTER: Ormseth MJ 

PROVIDER: S-EPMC11368629 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature