Endocan as a biomarker for acute respiratory distress syndrome: A systematic review and meta-analysis.

ABSTRACT:

Background and aims

Endocan is a marker of endothelial damage. Data regarding the association of this proteoglycan and acute respiratory distress syndrome (ARDS) is discrepant. Hence, this study sought to investigate the possible correlation between serum/plasma endocan concentration and ARDS.

Methods

A systematic review and meta-analysis of international online databases was conducted following PRISMA guidelines. PubMed, SCOPUS, Embase, and Web of Science were searched in March 2023, with the leading search terms being "ARDS" OR "respiratory distress" AND "endocan" and other associated terms. Studies that measured endocan levels in patients with ARDS and compared it with non-ARDS controls or within different severities of ARDS were included. We performed a random-effect met

SUBMITTER: Behnoush AH 

PROVIDER: S-EPMC11368821 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature