Visual input regulates melanophore differentiation.

ABSTRACT:

Introduction

Developmental processes continue in organisms in which sensory systems have reached functional maturity, however, little research has focused on the influence of sensory input on cell and tissue development. Here, we explored the influence of visual system activity on the development of skin melanophores in Xenopus laevis.

Methods

Melanophore number was measured in X. laevis larvae after the manipulation of visual input through eye removal (enucleation) and/or incubation on a white or black substrate at the time when the visual system becomes functional (stage 40). To determine the developmental process impacted by visual input, migration, proliferation and differentiation of melanophores was assessed. Finally, the role of melatonin in driving melanophore

SUBMITTER: Atkinson-Leadbeater K 

PROVIDER: S-EPMC11368843 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature