Psychometric evaluation of the Dysphagia Symptom Questionnaire for adults and adolescents with eosinophilic esophagitis.

ABSTRACT:

Background

Eosinophilic esophagitis (EoE) is a chronic, inflammatory disease of the esophagus leading to symptoms of esophageal dysfunction; dysphagia is the most common symptom experienced by adults and adolescents.

Objective

We sought to perform a psychometric evaluation of the Dysphagia Symptom Questionnaire (DSQ), a patient-reported outcome measure for patients with EoE.

Methods

Using baseline and week 24 data from the randomized, interventional, multinational phase 3 R668-EE-1774 trial (NCT03633617), the measurement properties of the DSQ-including reliability, construct and known-groups validity, responsiveness, and interpretation of change-were evaluated.

Results

The analysis population comprised 239 patients with EoE (age [mean ± SD], 28.1 ± 13.14 years;

SUBMITTER: McCann E 

PROVIDER: S-EPMC11369371 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature