Impairments in knowledge of social norms in presymptomatic, prodromal, and symptomatic frontotemporal dementia.

ABSTRACT:

Introduction

We aimed to assess the knowledge of social norms in patients with behavioral variant frontotemporal dementia (bvFTD) with the Dutch version of the Social Norms Questionnaire (SNQ-NL).

Methods

The SNQ-NL was administered in 34 patients with bvFTD, 20 prodromal mutation carriers, 76 presymptomatic mutation carriers, and 56 controls. Group differences and correlations with other neuropsychological tests and gray matter volume were examined.

Results

Patients with bvFTD had lower total SNQ-NL scores and more over-adherence errors than presymptomatic mutation carriers and controls (P < 0.001). SNQ-NL performance correlated with tests for executive functioning and social cognition, and with gray matter volume in bilateral frontal and unilateral temporal r

SUBMITTER: de Boer L 

PROVIDER: S-EPMC11369490 | biostudies-literature | 2024 Jul-Sep

REPOSITORIES: biostudies-literature