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ABSTRACT: Background
Following the introduction of rotavirus immunization in 2006 in the United States, there were substantial declines in the domestic rotavirus disease burden. In this study, we assess the value for money achieved by the program in the decade following vaccine introduction.Methods
We applied an age-specific, static, multicohort compartmental model to examine the impact and cost-effectiveness of the US rotavirus immunization program in children <5 years of age using healthcare utilization data from 2001 to 2015 inclusive. We calculated the incremental cost-effectiveness ratio (ICER) per quality-adjusted life year (QALY) gained from both a healthcare system and societal perspective.Results
Declines in healthcare use associated with the rotavirus and acute gast
SUBMITTER: Newall AT
PROVIDER: S-EPMC11369758 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature