The RELAX randomized controlled trial: Stretching versus meditation for nocturnal muscle cramps.

ABSTRACT:

Background

Muscle cramps are common among persons with cirrhosis and are associated with poor health-related quality of life (HRQOL). Treatment options are limited. We compared stretching or meditation in a randomized-controlled trial (RCT).

Patients

We enrolled 98 patients with a history of >4 muscle cramps in the prior month from 7/22-7/23. We randomized patients 1:1 to stretching versus meditation for 35 days. Our primary outcome was the change in cramp severity measured by the visual analogue scale for cramps (VAS-cramps, scaled 0-10). Secondary outcomes included a patient global impression of change (PGIC), change in sleep quality and global HRQOL measured using the EQ-5D and VAS-global HRQOL.

Results

Overall, 48% of patients had cirrhosis, 40% had diabetes, 16%

SUBMITTER: Tapper EB 

PROVIDER: S-EPMC11369850 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature