Reporting quality and risk of bias of randomized controlled trials of Chinese herbal medicine for multiple sclerosis.

ABSTRACT:

Background

Multiple sclerosis (MS) is the most common non-traumatic disabling disease affecting young adults. A definitive curative treatment is currently unavailable. Many randomized controlled trials (RCTs) have reported the efficacy of Chinese herbal medicine (CHM) on MS. Because of the uncertain quality of these RCTs, the recommendations for routine use of CHM for MS remain inconclusive. The comprehensive evaluation of the quality of RCTs of CHM for MS is urgent.

Methods

Nine databases, namely, PubMed, Embase, Web of Science, Cochrane Library, EBSCO, Sinomed, Wanfang Database, China National Knowledge Infrastructure, and VIP Database, were searched from inception to September 2023. RCTs comparing CHM with placebo or pharmacological interventions for MS were considered el

SUBMITTER: Wu JY 

PROVIDER: S-EPMC11369894 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature