Antivirals for post-exposure prophylaxis of influenza: a systematic review and network meta-analysis.

ABSTRACT:

Background

Antiviral post-exposure prophylaxis with neuraminidase inhibitors can reduce the incidence of influenza and the risk of symptomatic influenza, but the efficacy of the other classes of antiviral remains unclear. To support an update of WHO influenza guidelines, this systematic review and network meta-analysis evaluated antiviral drugs for post-exposure prophylaxis of influenza.

Methods

We systematically searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature, Global Health, Epistemonikos, and ClinicalTrials.gov for randomised controlled trials published up to Sept 20, 2023 that evaluated the efficacy and safety of antivirals compared with another antiviral or placebo or standard care for pre

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC11369964 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature