Robustness and variability in <i>Caenorhabditis elegans dauer</i> gene expression.

ABSTRACT: Both plasticity and robustness are pervasive features of developmental programs. The dauer in Caenorhabditis elegans is an arrested, hypometabolic alternative to the third larval stage of the nematode. Dauers undergo dramatic tissue remodeling and extensive physiological, metabolic, behavioral, and gene expression changes compared to conspecifics that continue development and can be induced by several adverse environments or genetic mutations that act as independent and parallel inputs into the larval developmental program. Therefore, dauer induction is an example of phenotypic plasticity. However, whether gene expression in dauer larvae induced to arrest development by different genetic or environmental triggers is invariant or varies depending on their route into dauer has not bee

SUBMITTER: Corchado JC 

PROVIDER: S-EPMC11370353 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature