Association of peripheral eosinophil count with chronic kidney disease progression risk: a retrospective cohort study in Chinese population.

ABSTRACT:

Background

The role of peripheral eosinophils in chronic kidney disease (CKD) requires further evaluation. We aimed to determine whether an eosinophil count increase is related to the occurrence of end-stage renal disease (ESRD).

Methods

This single-center, observational, retrospective cohort study was conducted between January 2016 and December 2018 in Hangzhou, China, and included 3163 patients, categorized into four groups according to peripheral eosinophil count (PEC) quartile values. The main outcome was ESRD development during follow-up. We evaluated the relationship between the serum eosinophil count, demographic and clinical information, and ESRD incidence. Cox proportional hazards models and Kaplan-Meier survival curves were used.

Results

A total of 3163 pati

SUBMITTER: Ren Y 

PROVIDER: S-EPMC11370690 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature