Association of Cancer and Its Interaction with Conventional Risk Factors on Cardiovascular Disease Risk.

ABSTRACT:

Introduction

We sought to examine the association of cancer history with the incidence of individual cardiovascular disease events and to clarify whether the history of cancer modifies the relationship between conventional cardiovascular risk factors and incident cardiovascular disease.

Methods

This retrospective cohort study used the JMDC Claims Database, including 3,531,683 individuals. The primary endpoint was the composite cardiovascular disease outcome, which included myocardial infarction, angina pectoris, stroke, heart failure, and atrial fibrillation.

Results

During a follow-up, 144,162 composite endpoints were recorded. Individuals with a history of cancer had a higher risk of developing composite cardiovascular disease events (hazard ratio [HR] 1.26, 95% con

SUBMITTER: Suzuki Y 

PROVIDER: S-EPMC11370727 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature