Meta-analysis: Prevalence and impact of alcohol abstinence in alcohol-associated cirrhosis.

ABSTRACT:

Background

Although alcohol abstinence may be an effective intervention for alcohol-associated cirrhosis, its association with prognosis has not been systematically assessed or quantified.

Aims

To determine the prevalence of alcohol abstinence, factors associated with alcohol abstinence and the impact of abstinence on morbidity and overall survival in people with alcohol-associated cirrhosis.

Methods

We searched Medline and Embase from inception to 15 April 2023 for prospective and retrospective cohort studies describing alcohol abstinence in people with known alcohol-associated cirrhosis. Meta-analysis of proportions for pooled estimates was performed. The method of inverse variance, employing a random-effects model, was used to pool the hazard ratio (HR) comparing o

SUBMITTER: Lim WH 

PROVIDER: S-EPMC11371415 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature