Maternal Exposure to Heavy Metals From Industrial Sources During Pregnancy and Childhood Cancer Risk in California.

ABSTRACT:

Objective

The study investigated maternal exposure to heavy metals from industrial sources during pregnancy as potential risk factors for childhood cancer.

Methods

Cases ages 0-19 were identified from California Cancer Registry. Controls (20:1 ratio) were randomly selected from California Birth Registry, frequency-matched by birth year (1998-2016). We estimated maternal exposure to lead, nickel, and cobalt in ambient air from the Toxics Release Inventory. We examined "ever/never" and "high/low" exposures categorized by median exposure. Models were adjusted for maternal age, race/ethnicity, method of payment for prenatal care, neighborhood socioeconomic status, and urban/rural residence.

Results

Among highly exposed persons, lead was associated with an increased terato

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11371530 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature