Short-term HIIT impacts HDL function differently in lean, obese, and diabetic subjects.

ABSTRACT:

Introduction

High density lipoproteins (HDL) exert cardiovascular protection in part through their antioxidant capacity and cholesterol efflux function. Effects of exercise training on HDL function are yet to be well established, while impact on triacylglycerol (TG)-lowering has been often reported. We previously showed that a short-term high-intensity interval training (HIIT) program improves insulin sensitivity but does not inhibit inflammatory pathways in immune cells in insulin-resistant subjects. The purpose of this study is to evaluate HDL function along with changes of lipoproteins after the short-term HIIT program in lean, obese nondiabetic, and obese type 2 diabetic (T2DM) subjects.

Methods

All individuals underwent a supervised 15-day program of alternative HIIT fo

SUBMITTER: Zhu L 

PROVIDER: S-EPMC11371628 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature