Investigating how blood cadmium levels influence cardiovascular health scores across sexes and dose responses.

ABSTRACT:

Background

The association between exposure to cadmium (Cd) and cardiovascular health (CVH) has received considerable scientific interest. However, findings thus far have been inconclusive, particularly regarding sex-specific effects and dose-response relationships. The aim of our study was to investigate the relationships of blood Cd levels with the overall and component CVH scores.

Methods

We used data from the 2011-2018 NHANES to assess CVH using indicators such as BMI, blood pressure, lipid profiles, glucose levels, diet, physical activity, nicotine use, and sleep quality, each rated on a 0-100 scale. The overall CVH score was calculated as the average of these indicators. We employed both multiple linear and restricted cubic spline analyses to examine the relationship b

SUBMITTER: Chen F 

PROVIDER: S-EPMC11371710 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature