Potential of animal-welfare compliant and sustainably sourced serum from pig slaughter blood.

ABSTRACT: The animal product most used as a stimulatory additive for cell cultivation is still fetal bovine serum (FBS). Besides the ethical concerns regarding serum collection, the main problems of FBS are batch-to-batch variability and the resulting risk of lower reproducibility, the differences between species, the presence of undefined/unknown components, and the risk of contamination. In contrast, pig blood, which is a by-product of slaughter, is a sufficiently available and sustainable resource with a high degree of standardization in terms of donor age, weight, and genetics. The variations in preparations from pig slaughter blood seem to be comparatively low, and consequently, batch effects might be much smaller, suggesting that the reproducibility of the research data obtained may be increas

SUBMITTER: Hahn O 

PROVIDER: S-EPMC11371839 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature