Heart rate variability: reference values and role for clinical profile and mortality in individuals with heart failure.

ABSTRACT:

Aims

To establish reference values and clinically relevant determinants for measures of heart rate variability (HRV) and to assess their relevance for clinical outcome prediction in individuals with heart failure.

Methods

Data from the MyoVasc study (NCT04064450; N = 3289), a prospective cohort on chronic heart failure with a highly standardized, 5 h examination, and Holter ECG recording were investigated. HRV markers were selected using a systematic literature screen and a data-driven approach. Reference values were determined from a healthy subsample. Clinical determinants of HRV were investigated via multivariable linear regression analyses, while their relationship with mortality was investigated by multivariable Cox regression analyses.

Results

Holter ECG recordi

SUBMITTER: Zeid S 

PROVIDER: S-EPMC11371886 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature