Prognostic value of temporal patterns of left atrial reservoir strain in patients with heart failure with reduced ejection fraction.

ABSTRACT:

Background

We investigated whether repeatedly measured left atrial reservoir strain (LASr) in heart failure with reduced ejection fraction (HFrEF) patients provides incremental prognostic value over a single baseline LASr value, and whether temporal patterns of LASr provide incremental prognostic value over temporal patterns of other echocardiographic markers and NT-proBNP.

Methods

In this prospective observational study, 153 patients underwent 6-monthly echocardiography, during a median follow-up of 2.5 years. Speckle tracking echocardiography was used to measure LASr. Hazard ratios (HRs) were calculated for LASr from Cox models (baseline) and joint models (repeated measurements). The primary endpoint (PEP) comprised HF hospitalization, left ventricular assist device, heart

SUBMITTER: Abou Kamar S 

PROVIDER: S-EPMC11371887 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature