Apelin (APLN) is a biomarker contributing to the diagnosis and prognosis of hepatocellular carcinoma.

ABSTRACT: Liver cancer, classified as a malignant hepatic tumor, can be divided into two categories: primary, originating within the liver, and secondary, resulting from metastasis to the liver from other organs. Hepatocellular carcinoma (HCC) is the main form of primary liver cancer and the third leading cause of cancer-related deaths. The diagnosis and prognosis of HCC using current methods still face numerous challenges. This study aims to develop novel diagnostic and prognostic models while identifying new biomarkers for improved HCC treatment. Diagnostic and prognostic models for HCC were constructed using traditional binary classification methods and machine learning algorithms based on the TCGA database (Downloaded in August 2023). The mechanisms by which APLN (Apelin) affects HCC were invest

SUBMITTER: Mao X 

PROVIDER: S-EPMC11371925 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature