Cardiac Substructure Radiation Dose and Associations With Tachyarrhythmia and Bradyarrhythmia After Lung Cancer Radiotherapy.

ABSTRACT:

Background

Arrhythmias are common following radiotherapy for non-small cell lung cancer.

Objectives

The aim of this study was to analyze the association of distinct arrhythmia classes with cardiac substructure radiotherapy dose.

Methods

A retrospective analysis was conducted of 748 patients with locally advanced non-small cell lung cancer treated with radiotherapy. Cardiac substructure dose parameters were calculated. Receiver-operating characteristic curve analyses for predictors of Common Terminology Criteria for Adverse Events grade ≥3 atrial fibrillation (AF), atrial flutter, non-AF and non-atrial flutter supraventricular tachyarrhythmia (SVT), bradyarrhythmia, and ventricular tachyarrhythmia (VT) or asystole were calculated. Fine-Gray regression models were perfo

SUBMITTER: Atkins KM 

PROVIDER: S-EPMC11372031 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature