Computer tomography-based assessment of perivascular adipose tissue in patients with abdominal aortic aneurysms.

ABSTRACT: This retrospective study investigates perivascular adipose tissue (PVAT) alterations in CT as a marker of inflammation in patients with abdominal aortic aneurysms (AAA). 100 abdominal CT scans of patients with abdominal aortic aneurysms and 100 age and sex matched controls without underlying aortic disease were included. Artificial Intelligence (AI) assisted segmentation of the aorta and the surrounding adipose tissue was performed. Adipose tissue density was measured in Hounsfield units (HU) close (2-5mm, HU_close) and distant (10-12mm, HU_distant) to the aortic wall. To investigate alterations in adipose tissue density close to the aorta (HU_close) as a potential marker of inflammation, we calculated the difference HU_Δ = HU_close-HU

SUBMITTER: Ginzburg D 

PROVIDER: S-EPMC11372190 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature