MASTering systemic mastocytosis: Lessons learned from a large patient cohort.

ABSTRACT:

Background

Systemic mastocytosis (SM), a rare condition affecting about 32,000 individuals in the United States, is often misdiagnosed or underdiagnosed owing to its nonspecific symptoms and the need for invasive biopsies.

Objective

Our aim was to identify, classify, and characterize the natural history of patients with SM.

Methods

In a retrospective cohort study, administrative data from a large managed care organization was used to identify patients with confirmed SM, based on World Health Organization criteria. Demographic data, delay to diagnosis, disease progression, and health care resource utilization were examined.

Results

Of 116 patients with confirmed SM, 77% had indolent SM, 2% had smoldering SM, 12% had SM with associated hematologic neoplasm, 9% ha

SUBMITTER: Tse KY 

PROVIDER: S-EPMC11372574 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature