Enrollment of underserved racial and ethnic populations in pediatric asthma clinical trials.

ABSTRACT:

Background

The existing data on enrollment trends of historically underserved racial and ethnic children in clinical trials are limited.

Objective

We sought to evaluate documentation and representation of race and ethnicity in pediatric asthma clinical trials in the United States.

Methods

This is a cross-sectional study of United States-based interventional trials studying pediatric asthma that were completed between 2008 and 2022 and registered on ClinicalTrials.gov. Enrollment disparities were assessed by using the measure enrollment prevalence difference (EPD) (defined as the median difference between the proportion of participants enrolled and asthma prevalence in the US population by race and ethnicity).

Results

Of the 67 trials reviewed, 53 (79.2%) and 36

SUBMITTER: Geanacopoulos AT 

PROVIDER: S-EPMC11372584 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature