Cost-effectiveness of a precision hepatocellular carcinoma surveillance strategy in patients with cirrhosis.

ABSTRACT:

Background

Hepatocellular carcinoma (HCC) surveillance is currently performed using a one-size-fits-all strategy with ultrasound plus AFP (US + AFP). There is increasing interest in risk-stratified and precision surveillance strategies incorporating individual risk and variance in surveillance test performance; however, the cost-effectiveness of these approaches has not been evaluated.

Methods

We conducted a cost-effectiveness analysis to evaluate four surveillance strategies (no surveillance, universal US + AFP surveillance, risk-stratified surveillance, and precision surveillance) in a simulated cohort of 50-year-old patients with compensated cirrhosis. The most cost-effective strategy was that with the highest incremental cost-effectiveness ratio (ICER) and below the will

SUBMITTER: Kao SZ 

PROVIDER: S-EPMC11372615 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature