Frailty and anticoagulants in older subjects with atrial fibrillation: the EUROSAF study.

ABSTRACT:

Aims

Literature regarding anticoagulants in older people affected by atrial fibrillation (AF) is limited to retrospective studies, poorly considering the importance of multidimensional frailty. The main objective of this study is to evaluate in hospitalised older persons with AF the benefit/risk ratio of the anticoagulant treatments, considering the severity of frailty, determined by the multidimensional prognostic index (MPI).

Methods

In this European, multicentre, prospective study, older hospitalised patients (≥65 years) with non-valvular AF were followed-up for 12 months. Anticoagulants' use at discharge ascertained using medical records. MPI was calculated using tools derived from comprehensive geriatric assessment, classifying participants in robust, pre-frail or frail

SUBMITTER: Pilotto A 

PROVIDER: S-EPMC11373113 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature