Advancements in cell-based therapies for thermal burn wounds: a comprehensive systematic review of clinical trials outcomes.

ABSTRACT:

Background

Burn trauma is one of the major causes of morbidity and mortality worldwide. The standard management of burn wounds consists of early debridement, dressing changes, surgical management, and split-thickness skin autografts (STSGs). However, there are limitations for the standard management that inclines us to find alternative treatment approaches, such as innovative cell-based therapies. We aimed to systematically review the different aspects of cell-based treatment approaches for burn wounds in clinical trials.

Methods

A systematic search through PubMed, Medline, Embase, and Cochrane Library databases was carried out using a combination of keywords, including "Cell transplantation", "Fibroblast", "Keratinocyte", "Melanocyte", or "Stem Cell" with "Burn", "Burn woun

SUBMITTER: Yassaghi Y 

PROVIDER: S-EPMC11373270 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature