Risk of metachronous neoplasia in early-onset colorectal cancer: meta-analysis.

ABSTRACT:

Background

Metachronous colorectal cancer refers to patients developing a second colorectal neoplasia diagnosed at least 6 months after the initial cancer diagnosis, excluding recurrence. The aim of this systematic review is to assess the incidence of metachronous colorectal cancer in early-onset colorectal cancer (defined as age at diagnosis of less than 50 years) and to identify risk factors.

Methods

This is a systematic review and meta-analysis performed following the PRISMA statement and registered on PROSPERO. The literature search was conducted in PubMed and Embase. Only studies involving patients with early-onset colorectal cancer (less than 50 years old) providing data on metachronous colorectal cancer were included in the analysis. The primary endpoint was the risk

SUBMITTER: Pellino G 

PROVIDER: S-EPMC11373379 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature