Impact of Skin Care Products on Phthalates and Phthalate Replacements in Children: the ECHO-FGS.

ABSTRACT:

Background

Phthalates and their replacements have been implicated as developmental toxicants. Young children may be exposed to phthalates/replacements when using skin care products (SCPs).

Objectives

Our objective is to assess the associations between use of SCPs and children's urinary phthalate/replacement metabolite concentrations.

Methods

Children (4-8 years old) from the Environmental Influences on Child Health Outcomes-Fetal Growth Study (ECHO-FGS) cohort provided spot urine samples from 2017 to 2019, and mothers were queried about children's SCP use in the past 24 h (n=906). Concentrations of 16 urinary phthalate/replacement metabolites were determined by liquid chromatography-tandem mass spectrometry (n=630). We used linear regression to estimate the child's us

SUBMITTER: Bloom MS 

PROVIDER: S-EPMC11373421 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature