Dataset Information

Deep Learning to Predict Mortality After Cardiothoracic Surgery Using Preoperative Chest Radiographs.

ABSTRACT:

Background

The Society of Thoracic Surgeons Predicted Risk of Mortality (STS-PROM) estimates mortality risk only for certain common procedures (eg, coronary artery bypass or valve surgery) and is cumbersome, requiring greater than 60 inputs. We hypothesized that deep learning can estimate postoperative mortality risk based on a preoperative chest radiograph for cardiac surgeries in which STS-PROM scores were available (STS index procedures) or unavailable (non-STS index procedures).

Methods

We developed a deep learning model (CXR-CTSurgery) to predict postoperative mortality based on preoperative chest radiographs in 9283 patients at Massachusetts General Hospital (MGH) having cardiac surgery before April 8, 2014. CXR-CTSurgery was tested on 3615 different MGH patients and externally tested on 2840 patients from Brigham and Women's Hospital (BWH) having surgery after April 8, 2014. Discrimination for mortality was compared with the STS-PROM using the C-statistic. Calibration was assessed using the observed-to-expected ratio (O/E ratio).

Results

For STS index procedures, CXR-CTSurgery had a C-statistic similar to STS-PROM at MGH (CXR-CTSurgery: 0.83 vs STS-PROM: 0.88; P = .20) and BWH (0.74 vs 0.80; P = .14) testing cohorts. The CXR-CTSurgery C-statistic for non-STS index procedures was similar to STS index procedures in the MGH (0.87 vs 0.83) and BWH (0.73 vs 0.74) testing cohorts. For STS index procedures, CXR-CTSurgery had better calibration than the STS-PROM in the MGH (O/E ratio: 0.74 vs 0.52) and BWH (O/E ratio: 0.91 vs 0.73) testing cohorts.

Conclusions

CXR-CTSurgery predicts postoperative mortality based on a preoperative CXR with similar discrimination and better calibration than the STS-PROM. This may be useful when the STS-PROM cannot be calculated or for non-STS index procedures.

SUBMITTER: Raghu VK

PROVIDER: S-EPMC11373441 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Publications

Deep Learning to Predict Mortality After Cardiothoracic Surgery Using Preoperative Chest Radiographs.

Raghu Vineet K VK Moonsamy Philicia P Sundt Thoralf M TM Ong Chin Siang CS Singh Sanjana S Cheng Alexander A Hou Min M Denning Linda L Gleason Thomas G TG Aguirre Aaron D AD Lu Michael T MT

The Annals of thoracic surgery 20220521 1

<h4>Background</h4>The Society of Thoracic Surgeons Predicted Risk of Mortality (STS-PROM) estimates mortality risk only for certain common procedures (eg, coronary artery bypass or valve surgery) and is cumbersome, requiring greater than 60 inputs. We hypothesized that deep learning can estimate postoperative mortality risk based on a preoperative chest radiograph for cardiac surgeries in which STS-PROM scores were available (STS index procedures) or unavailable (non-STS index procedures).<h4>M ...[more]

PMID: 35609650

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Dataset Information

Deep Learning to Predict Mortality After Cardiothoracic Surgery Using Preoperative Chest Radiographs.

Background

Methods

Results

Conclusions

Publications

Deep Learning to Predict Mortality After Cardiothoracic Surgery Using Preoperative Chest Radiographs.

Similar Datasets

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