Testing times: disentangling admixture histories in recent and complex demographies using ancient DNA.

ABSTRACT: Our knowledge of human evolutionary history has been greatly advanced by paleogenomics. Since the 2020s, the study of ancient DNA has increasingly focused on reconstructing the recent past. However, the accuracy of paleogenomic methods in resolving questions of historical and archaeological importance amidst the increased demographic complexity and decreased genetic differentiation remains an open question. We evaluated the performance and behavior of two commonly used methods, qpAdm and the f3-statistic, on admixture inference under a diversity of demographic models and data conditions. We performed two complementary simulation approaches-firstly exploring a wide demographic parameter space under four simple demographic models of varying complexities and configurations using branch-length

SUBMITTER: Williams MP 

PROVIDER: S-EPMC11373510 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature