Preoperative glucose in surgical oncology patient is not associated with postoperative outcomes after adjustment for frailty.

ABSTRACT:

Background

Observational studies have shown associations between even small elevations in preoperative glucose and poorer outcomes, including increased length of stay (LOS) and higher mortality. This has led to calls for aggressive glycemic control in the preoperative period, including delay of treatment until glucose is reduced. However, it is not known whether there is a direct causal effect of blood glucose or whether adverse outcomes result from overall poorer health in patients with higher glucose.

Methods

Analysis was performed using a retrospective database of patients aged 65 and older who underwent cancer surgery. The last measured preoperative glucose was the exposure variable. The primary outcome was extended LOS (>4 days). Secondary outcomes included mortality, a

SUBMITTER: Huang A 

PROVIDER: S-EPMC11373875 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature