Neonatal risk factors associated with autism spectrum disorders: an umbrella review.

ABSTRACT:

Background

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by severe social communication deficits and stereotypical repetitive behaviors.

Purpose

This umbrella review assessed neonatal risk factors associated with ASD using meta-analyses and systematic reviews.

Methods

We conducted a systematic search of interna- tional databases including PubMed, Scopus, and Web of Science for studies published through April 2022 utilizing pertinent keywords. A random-effects model was used to calculate the odds ratio (OR) and 95% confidence interval (CI). Substantial heterogeneity was considered at values of I2≥50%. A quality assessment of the included studies was performed using the A MeaSurement Tool to Assess Systematic Reviews (AMSTAR2) checklist.

SUBMITTER: Salehi AM 

PROVIDER: S-EPMC11374450 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature