Long-term tracking of glycosylated hemoglobin levels across the lifespan in type 1 diabetes: from infants to young adults.

ABSTRACT:

Purpose

Glycosylated hemoglobin (HbA1c) is commonly used as a monitoring tool in diabetes. Due to the potential influence of insulin resistance (IR), HbA1c level may fluctuate over a person's lifetime. This study explores the long-term tracking of HbA1c level in individuals diagnosed with type 1 diabetes mellitus (T1DM) from infancy to early adulthood.

Methods

The HbA1c levels in 275 individuals (121 males, 43.8%) diagnosed with T1DM were tracked for an average of 9.4 years. The distribution of HbA1c levels was evaluated according to age with subgroups divided by gender, use of continuous glucose monitoring (CGM), and the presence of complications.

Results

HbA1c levels were highest at the age of 1 year and then declined until age 4, followed by a significant increase,

SUBMITTER: Kim S 

PROVIDER: S-EPMC11374514 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature