Associations between SII, SIRI, and cardiovascular disease in obese individuals: a nationwide cross-sectional analysis.

ABSTRACT:

Background

Systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) are comprehensive markers of inflammatory status. However, the correlation between SII and SIRI and the prevalence of cardiovascular disease (CVD) in populations with obesity remains unknown.

Methods

This is a cross-sectional study with data obtained from the National Health and Nutrition Examination Survey from 1999 to 2018. SII and SIRI were calculated using the following equations: SII = (platelet count × neutrophil count)/lymphocyte count. SIRI = (neutrophil count × monocyte count)/lymphocyte count. Spearman's rank correlation coefficient was used to assess the relationship between SII and SIRI and baseline variables. Logistic regression models and generalized additive mod

SUBMITTER: Liu Z 

PROVIDER: S-EPMC11374596 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature