Mechanical ventilation settings during weaning from venovenous extracorporeal membrane oxygenation.

ABSTRACT:

Background

The optimal timing of weaning from venovenous extracorporeal membrane oxygenation (VV ECMO) and its modalities have been rarely studied.

Methods

Retrospective, multicenter cohort study over 7 years in two tertiary ICUs, high-volume ECMO centers in France and Italy. Patients with ARDS on ECMO and successfully weaned from VV ECMO were classified based on their mechanical ventilation modality during the sweep gas-off trial (SGOT) with either controlled mechanical ventilation or spontaneous breathing (i.e. pressure support ventilation). The primary endpoint was the time to successful weaning from mechanical ventilation within 90 days post-ECMO weaning.

Results

292 adult patients with severe ARDS were weaned from controlled ventilation, and 101 were on spontaneo

SUBMITTER: Passarelli MT 

PROVIDER: S-EPMC11374948 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature