Enabling SENSE accelerated 2D CSI for hyperpolarized carbon-13 imaging.

ABSTRACT: As hyperpolarized (HP) carbon-13 (¹³C) metabolic imaging is clinically translated, there is a need for easy-to-implement, fast, and robust imaging techniques. However, achieving high temporal resolution without decreasing spatial and/or spectral resolution, whilst maintaining the usability of the imaging sequence is challenging. Therefore, this study looked to accelerate HP ¹³C MRI by combining a well-established and robust sequence called two-dimensional Chemical Shift Imaging (2D CSI) with prospective under sampling and SENSitivity Encoding (SENSE) reconstruction. Due to the low natural abundance of ¹³C, the sensitivity maps cannot be pre-acquired for the reconstruction. As such, the implementation of sodium (²³Na) sensitivity maps for SENSE re

SUBMITTER: Shinozaki A 

PROVIDER: S-EPMC11375102 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature