Blood Pressure and Cardiovascular Risk in Women With Breast Cancer: The Pathways Heart Study.

ABSTRACT:

Background

Hypertension is an important contributor to cardiovascular disease (CVD) in breast cancer (BC) survivors; however, research on blood pressure (BP) and CVD outcomes in BC survivors is limited.

Objectives

The purpose of this study was to better characterize the association between BP and CVD in a large, longitudinal cohort of BC patients.

Methods

Women with invasive BC diagnosed from 2005 to 2013 at Kaiser Permanente Northern California were matched 1:5 to women without BC. Patient data were obtained from electronic health records. Multivariable Cox regression and penalized spline models were used to explore the linear and nonlinear relationship of systolic blood pressure (SBP) and diastolic blood pressure (DBP) on CVD outcomes.

Results

BC cases (n = 1

SUBMITTER: Leedy DJ 

PROVIDER: S-EPMC11375265 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature